Semaglutide is a synthetic GLP-1 receptor agonist peptide that mimics the human glucagon-like peptide-1 (GLP-1) hormone, regulating blood sugar and appetite.

Primarily used for Type 2 diabetes and weight management, it reduces food cravings by increasing satiety, slowing gastric emptying, and reducing caloric intake.

Key Aspects of Semaglutide Peptide

Mechanism: It acts as a long-acting analog of GLP-1, with 94% homology to the human hormone, allowing for once-weekly injections.
Weight Loss & Diabetes: It stimulates insulin secretion, suppresses glucagon release, and controls appetite in the brain.
Common Brand Names:
Marketed by the following names: Ozempic, Wegovy and Rybelsus.
Structure: It is a modified peptide with a long fatty acid chain that extends its half-life to about 7 days.
Benefits: Beyond weight loss and glycemic control, research shows it reduces the risk of major adverse cardiovascular events (heart attack, stroke).