5-Amino-1MQ is a potent research peptide inhibitor studied for reversing high-fat diet-induced obesity and treating metabolic syndrome. It works by reducing the activity of the NNMT enzyme, thereby increasing NAD+ levels and boosting cellular metabolism. It is sold only as a research peptide.

Function: Inhibits NNMT, a metabolic target for treating obesity and diabetes.
Mechanism: Improves metabolic rate by increasing NAD+ levels.
Application: Studied for the potential to increase energy expenditure and reduce body weight.

Metabolic Optimisation and NNMT Inhibition 5-Amino-1MQ is a small, permeable molecule that functions as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). This enzyme is primarily found in fat tissue and plays a significant role in regulating energy metabolism. By inhibiting NNMT, 5-Amino-1MQ allows for an increase in intracellular NAD+ levels, which are crucial for cellular energy production. In a research setting, this mechanism is highly valued for its potential to flip the "metabolic switch," encouraging the body to burn fat more efficiently while preventing the formation of new fat cells.

Supporting Muscle Maintenance and Performance Beyond its fat-burning capabilities, 5-Amino-1MQ is studied for its impact on muscle tissue integrity. Research indicates that by lowering NNMT activity, the compound can help promote the regeneration of muscle fibres and improve overall muscle contractility. This makes it a primary subject of interest for those exploring ways to maintain lean muscle mass during weight loss phases or to enhance physical endurance and recovery after high-intensity exercise.

Influence on Cellular Longevity and NAD+ Levels The relationship between NNMT and NAD+ is a critical focus of longevity research. As NNMT levels increase with age, they deplete the body’s supply of NAD+, leading to decreased mitochondrial function and cellular aging. By suppressing this enzyme, 5-Amino-1MQ helps sustain higher levels of NAD+, supporting mitochondrial health and cellular repair processes. This systemic approach to metabolic health makes it a versatile tool for researchers looking into age-related metabolic decline and vitality.

Neuroprotective and Cardiovascular Potential Emerging studies suggest that the benefits of 5-Amino-1MQ may extend to the cardiovascular and nervous systems. By improving metabolic markers such as cholesterol levels and insulin sensitivity, it contributes to better heart health and more stable energy levels throughout the day. Furthermore, the increase in cellular energy efficiency may offer neuroprotective benefits, assisting the brain in maintaining cognitive function and resilience against metabolic stress.

Product Quality and Storage Guidelines This 5 mg vial of 5-Amino-1MQ is produced to the highest standards of purity through advanced molecular synthesis. To maintain the structural stability of the compound, it is supplied in a lyophilised (freeze-dried) state. For optimal preservation, the vial should be stored in a cool, dark environment or refrigerated at 2°C to 8°C. Ensuring the product remains away from moisture and direct sunlight will guarantee the reliability and consistency of research results across all applications.